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Regulatory environment (external): Active uncertainty - FDA's April 2026 proposal to restrict 503B compounding remains open for public comment through June 29, 2026

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In addition to these tissues, emerging data suggest that GLP-1-based therapies possess anti-inflammatory effects on the liver, brain, kidney, lung, testis, skin, and vascular system including aorta and vein endothelial cells, by reducing the production of inflammatory cytokines and infiltration of immune cells in the tissues 19,24

Lancet 402 (10414), 17881801

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