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It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile
Sterile water has no preservative, meaning that every time you puncture the stopper, you risk introducing bacteria that can then thrive in the vial
Through these integrated regulatory measures, the body is able to maintain carnitine pool homeostasis under different physiological and environmental conditions (Fig
And so I published all this in a review in Experimental Gerontology, last year I guess, late last year