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A retrospective cohort study published in JAMA Oncology (n=86,632) found that adults with obesity taking GLP-1s had significantly reduced risk of overall cancer, particularly endometrial and ovarian cancers and meningioma, compared to non-GLP-1 users

But the AAOS data is from five years of real-world use, not a short-term trial, and the divergence may simply reflect that shorter-term effects on bone markers dont capture what happens over years of use

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Another common issue is incomplete paperwork - missing ICD-10 codes or a lack of supporting medical records can result in a rejection