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The approval of orforglipron signals both a shift toward more accessible obesity treatments and a test case for the FDAs new accelerated review pathway
PMID: 7569285.Iskusnykh IY, Zakharova AA, Pathak D
As early as the mid-20th century, studies of commercial diet programs showed that while short-term weight loss was common, regaining weight long term was the norm
95% confidence interval [CI]: 0.79-0.94
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