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Restricting cysteine, depleting GSH, or inhibiting GPX4 can increase phospholipid peroxidation in responsive cells, but sensitivity also depends on lipid composition, iron metabolism, parallel antioxidant systems, and tissue context (Jiang et al., 2021)

Temozolomide drives ferroptosis via a DMT1-dependent pathway in glioblastoma cells

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Additionally, it increased levels of glutathione peroxidase, a powerful antioxidant ( This indicates that selenium may help lower heart disease risk by reducing inflammation and oxidative stress in your body

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