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During off periods, your system has time to resensitize

GLP-1 stands for glucagon-like peptide-1 , a hormone naturally released in your gut after eating

It does this by mimicking the ghrelin and binding to the ghrelin receptor in the pituitary gland

Even within the same batch, some cells perform slightly better or worse

But they arguably wouldn't be here if it wasn't for Eng's work which created the very first GLP-1 drug

If you miss a semaglutide dose during the early transition (within the first 4 weeks), the impact is greater than missing a dose after reaching steady state because the drug has not yet accumulated to therapeutic levels