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As mentioned in the study, administration of exenatide after SCI suppressed C/EBP homologous transcription factor protein (CHOP, a pro-apoptotic transcription factor central to ER stress-mediated apoptosis) while upregulating glucose regulatory protein 78 (GRP78, an ER chaperone with cytoprotective effects) in the injured spinal cord, leading to a significant decrease in tissue damage and a significant increase in oligodendrocyte progenitor cell survival [66]
SSRP Institute: FDA Announces Change in Status of 12 Peptides CNBC: RFK Jr
T., Naveed, S., & Ashraf, N
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Aging Cell 18 (1), e12845
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