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However, the effect varies, is not guaranteed, and the evidence is still limited
The highest dose administered has been 300 mg/kg
we adjust if a cycle isnt doing what you expected, not on a fixed timeline
As a precursor of GSH, NAC not only facilitates de novo GSH synthesis but also exhibits independent antioxidant effects
Preclinical studies have suggested potential biomarkers such as circulating free IGF levels, mutations of p53, BRCA1, KRAS and BRAF, IRS2 copy number gain, InsR/IGF-IR overexpression, InsR/IGF-IR pathway activation, PTEN loss, CD24, mesenchymal markers, -catenin/TCF activity, FUS-DDIT3 fusion, and ERG [192,193,194,195,196,197,198,199,200,201]
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