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Chemically modified SOD2 mRNA lipid nanoparticles (LNPs) delivered via subcapsular injection achieve mitochondrial-targeted delivery, effectively inducing the expression of endogenous SOD2 protein in renal tubular epithelial cells, thereby enhancing mitochondrial SOD activity, reducing ROS production, and inhibiting apoptosis

The SGLT2 inhibitor dapagliflozin has been shown to decrease the risk of developing type 2 diabetes

These experiments indicate that flavonoids may subsequently be used as potential therapies for iron overload syndromes

Angiogenesis is essential for wound healing but can support the growth of tumors when cancer is present