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NNMT transfers a methyl group from S-adenosylmethionine (SAM) to nicotinamide (a form of vitamin B3), producing 1-methylnicotinamide
It increased survival of cultured enteric neurons and proliferation of enteric glial cells, suggesting direct neuroprotective effects on the enteric nervous system that could influence central serotonin tone through vagal signaling
Its antioxidant action also slows signs of aging by protecting against cellular damage and supporting detox
It plays a role in protecting cells from oxidative stress, recycling other antioxidants, and supporting normal liver detoxification pathways
Some users double the dose during periods of intense training or after physical strain, but it's always best to begin with the base dosage and adjust gradually
Integration in a clinic specialising in hormone replacement, body composition & regenerative medicine Tissue regeneration and body composition improvements (e.g., better muscle regeneration, improved organ function, less fibrosis) may be a compelling angle
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