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Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss
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In rare cases, bloating and stomach cramps have been reported during supplementation
HUBERMAN: And it's one for which we are just now really starting to appreciate how many different peptides the human body and brain make
These effects are called interactions
Additional Reading: Sikiric P, Seiwerth S, Romic Z, et al
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