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Accumulation of -synuclein causes stress in the endoplasmic reticulum and affects protein folding, leading to the unfolded protein response [9]

134 SasakiM.SasakoT.KubotaN.SakuraiY.TakamotoI.KubotaT.et al (2017)

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This indicates that a substantial part of the GSH pool is in an oxidized state in the gastrointestinal lumen, which is mainly related to the fact that intracellular levels of GSH and other components of the redox environment are more heavily regulated by the cell as compared to the redox environment of the extracellular space (48)