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Handling dose escalation side effects The transition periods, especially from 2mg to 4mg and from 4mg to 8mg, are where most side effects occur

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In this guide, youll learn how it works, what it can and cannot do, potential side effects, and how to use it safely with clinician guidance

The question is whether the full development package supports approval for the proposed use and label

doi: 10.1007/s12975-022-01064-x 91

To overcome CKs poor bioavailability, an albumin-based nanoformulation (nabCK) was developed for improved hepatic targeting