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After four weeks, evaluate whether symptoms have improved
Tirzepatide, on the other hand, activates both GLP-1 and GIP receptors
Food and Drug Administration (FDA) for treating type 2 diabetes
Between-study variance was quantified using Tau ()-squared, and heterogeneity was assessed with Cochrans Q and I -squared ( I 2 ), where I 2 50% indicated substantial heterogeneity
Based on results from the PIONEER project, oral semaglutide has been approved for treatment in patients with type 2 diabetes, where a 14 mg dose can reduce hemoglobin A1c (HbA1c) levels by up to 1.4% and lead to a weight loss of up to 4.4 kg
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