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10.1093/ajcn/80.1.108 140
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In laboratory settings, FOXO4-DRI is used as a research reagent for experimental systems examining FOXO4-p53 protein interaction disruption, senescent cell modeling, DNA damage signaling assays, and oxidative stress research
Next, the ability of 2012 to block tumor growth was evaluated in the B16F10 syngeneic mouse model of melanoma, in which tumor growth was shown to be sensitive to FAT domain mutation 40
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