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doi: 10.1016/j.freeradbiomed.2019.01.051 97 MauryaP

We show how cardiolipin, an anionic lipid synthesized in mitochondria and localized to the mitochondrial membrane, may play a central role both in trapping deuterium in the mitochondrial membrane and in inducing protein misfolding to facilitate the formation of deuterium-rich deposits

xCT/GPX4 pathway inhibits ferroptosis The core molecular mechanism of ferroptosis involves regulating the balance between oxidative stress and antioxidant defense [37]

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Richie et al