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10.1016/j.jns.2016.02.042 440 TroubatR.BaroneP.LemanS.DesmidtT.CressantA.AtanasovaB.et al
Primary Functions of GLP-1 Blood Sugar Regulation Enhances insulin secretion when glucose levels are high Reduces glucagon release to prevent excess glucose production Improves overall glycemic control Helps maintain stable blood sugar levels throughout the day Appetite and Weight Management Increases feelings of fullness and satiety Reduces hunger signals to the brain Decreases food intake Slows stomach emptying to prolong satisfaction after meals Cardiovascular Health Reduces blood pressure Improves heart function May reduce risk of cardiovascular events Supports healthy blood vessel function Neuroprotective Effects May protect brain cells from damage Potentially reduces inflammation in the nervous system Being studied for neurodegenerative conditions Why People Use GLP-1 Type 2 Diabetes Management: GLP-1 receptor agonists (medications that mimic GLP-1) are highly effective for controlling blood sugar in diabetic patients
When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations
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BMJ Open 2021;11:e051506 19
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