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Unopened pens must remain refrigerated at 36F to 46F until first use

Foods rich in Vitamin B12 include beef, liver, poultry, fish (like salmon and tuna), eggs, dairy products, and fortified cereals

Where direct clinical evidence is limited, mechanistic findings are interpreted as hypothesis-generating rather than causal, in order to avoid overextension of preclinical results

Current evidence suggests no direct bone toxicity, though weight reduction itself may influence bone metabolism

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