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Circulation 140 (7), e294e324
GLP-1R and GIPR belong to class B1 of the G protein-coupled receptors, and share high homology and a similar action pattern
Do not store it in the freezer door, where temperatures fluctuate wildly
The expression of NRF1 is highest in skeletal muscle which is also the tissue that accounts for the largest percentage of glucose disposal in the body and, therefore, is the tissue that is most responsible for the hyperglycemia resulting from impaired insulin signaling