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Pharoah BM, Zhang C, Khodade VS, Keceli G, McGinity C, Paolocci N, Toscano JP
The safety profile of microdosing is unknown
Figure 3c and Supplementary Fig
To allow for equilibration of the system, the intestine/colon was perfused for 25 min before initiation of the experimental protocol
Wollina, Uwe
The distinction matters because the slower titration to 2.4 mg produces better tolerability and lower discontinuation rates
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