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The VANQUISH-1 trial enrolled approximately 4,650 adults with overweight or obesity without diabetes, and the VANQUISH-2 trial is currently enrolling about 1,100 adults with type 2 diabetes plus overweight or obesity
While Ppg/GLP1-mediated neurotransmission plays a central role in the modest appetite-suppressing effects of GLP1NTS cells, additional pathways engaged by LepRbNTS cells dominate for the suppression of food intake
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Yes, although both commonly cause nausea or digestive discomfort, some people tolerate one medication better than the other.
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doi:10.1210/mend.16.1.0753
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