While I don't have a crystal ball to see the future, I do see hope on the horizon
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Peter, J
3dg and 3os (vehicle n = 8 mice, 100 nmol kg 1 MK-801 n = 8 mice, 100 nmol kg 1 GLP-1 n = 8 mice, 100 nmol kg 1 GLP-1MK-801 n = 8 mice)
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This is followed by the release of nesfatin-1 which stimulates cholecystokinin secretion leading to a rise in bile salts from gallbladder emptying, and the binding of Takeda P protein coupled receptor 5 (TGR5) onto the surface of the enteroendocrine cells, all of which eventually culminates in GLP-1 secretion [9]