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Acetyl-L-carnitine augmentation of clozapine in partial-responder schizophrenia: a 12-week, open-label uncontrolled preliminary study

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These fatty acids are extremely susceptible to oxidative damage by free radicals or Reactive Oxygen Species (ROS) by a process called lipid peroxidation (LPO)

reduce the occurrence of age-related neurodegenerative diseases such as Alzheimers disease (AD) and Parkinsons disease (Son et al., 2012)

When consumed as a standard powder or tablet, the fragile tripeptide structure is rapidly degraded by gastric enzymes (such as gamma-glutamyltransferase) and undergoes aggressive first-pass hepatic metabolism, reducing the amount of GSH in the blood [2]