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doi: 10.1017/jns.2019.29 68 WangZWangHChenYChenYZhangXDiwonAet al

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PE-22-28 inhibits TREK-1 with an IC50 of 0.12 nM, as determined by electrophysiology in HEK293 cells expressing human TREK-1

Zhang BB et al

More scientific study is needed to determine their efficacy