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Clinical Update 9/16/2022 Gluten & Dry Eye

Typically mild to moderate, peaking 1-3 days after dose increases and gradually subsiding over 1-2 weeks

Absorption across the gut epithelium, first-pass liver metabolism, and systemic distribution are all separate steps that determine whether an orally administered compound reaches target tissues at meaningful concentrations

Formulations using liposomal encapsulation, DMSO as a carrier solvent, or lipid-conjugated versions of the peptide (a strategy used commercially with palmitoyl peptides) can improve dermal delivery, but most mass-market glow peptide serums do not disclose which approach, if any, they use

While they share some overlapping areas of investigation, they differ significantly in structure, origin, and proposed mechanisms