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Lu, X., Yang, X
Without barriers such as digestion, the body absorbs 15-97% of the injected B12, making injections much more efficient at raising blood levels quickly even if the pill dose is higher
"But we were quite surprised that it was the number was as high as it was." Silverstein and his colleagues calculated the inappropriately prescribed shots needlessly cost the province's health-care system $45.6 million annually
If morning dosing is logistically impossible
First, the effect is enzymatic and cumulative you are shifting a metabolic set-point over days and weeks, not triggering an acute hormonal event, which is why steady daily exposure matters more than any single large dose
In diet-induced obese mice, studied for reductions in body weight, fat mass, and adipocyte size without altering food intake
