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Taking excess B12 can interfere with the effectiveness of certain other medicines, particularly diabetes medications Laser MD Medspa Not recommended for people with certain conditions like Leber's disease, cobalt allergies, or severe kidney problems

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Any discussion of biological activity refers solely to laboratory, in vitro, or preclinical research

A problem at any part along the way can impact the bioavailability of vitamin B12

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Also, individuals with COMT defects can be at higher risk for accumulating too much peroxynitrites which builds up in their bodies, causing stiffness and muscle pain or brain fog and cardiovascular problems