S2CID 37393683
when present, symptoms typically relate to underlying conditions such as liver disease, kidney dysfunction, or haematological disorders rather than the high B12 itself

Specific situations requiring medical review include: Severe or persistent gastrointestinal side effects from Mounjaro that significantly limit your food intake for more than a few days You are taking metformin in addition to Mounjaro, as this combination increases B12 deficiency risk You have a history of pernicious anaemia, gastric surgery, or conditions affecting nutrient absorption You are considering stopping B12 injections whilst taking Mounjaro You experience any unexplained neurological symptoms Urgent medical attention is needed if you develop severe, persistent abdominal pain (which may radiate to the back), persistent vomiting, fever, or yellowing of the skin/eyes, as these could indicate pancreatitis or gallbladder problems Your GP or practice nurse can arrange blood tests to check your B12 levels (serum B12, holotranscobalamin, and if borderline, methylmalonic acid levels may be used where available) and determine the appropriate frequency of B12 injections if deficiency is confirmed

Peer-reviewed studies relevant to AOD-9604 are listed in the Citations tab on this product page
And it can refer to a lack of iodine, selenium, and molybdenum which are the main reasons for not being able to activate B2
Annals of Clinical and Laboratory Science