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However, Ozempic is not FDA-approved specifically for weight loss

However, glucagon receptor agonism at carefully balanced levels has been proposed based on preclinical and early clinical data to increase energy expenditure, promote fat breakdown (lipolysis), and reduce liver fat content

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Increased oxidative stress is a defining feature of hyperthyroidism (89)

Mild to moderate nausea, whilst uncomfortable, is generally considered a manageable adverse effect that does not necessitate stopping treatment

This approval for Ozempic allows us to more broadly address conditions within cardiovascular-kidney-metabolic syndrome, which affects millions of adults and could have serious consequences if left untreated," said Anna Windle, PhD, Senior Vice President Clinical Development, Medical & Regulatory Affairs at Novo Nordisk