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RNA sequencing and bioinformatic analysis RNA was extracted from epididymal white adipose tissue using TRIzol reagent (Life Technologies, USA)

By acting on the brains appetite centers and the digestive tract, GLP-1 medications can: Suppress appetite and reduce food cravings Slow gastric emptying, making you feel fuller for longer Improve insulin sensitivity and stabilize blood sugar Support significant and sustained weight loss, sometimes rivaling bariatric surgery These medications are typically prescribed as weekly injections and are most effective when combined with healthy lifestyle changes

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doi: 10.1186/s12967-022-03328-4 78 SuYYuanDChenDGNgRHWangKChoiJet al