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Cooper, MD (AA, University of Iowa Roy J

[12] For total GST activity, CDNB is widely used as a general substrate, although it does not measure every GST isoform equally

However, its critical to emphasize that these findings stem exclusively from animal models and should not be extrapolated beyond the research context without further rigorous investigation

For example, NAC may be one such therapeutic strategy as it restores GSH and has been investigated as a therapeutic agent in adults with various neuropsychiatric disorders (40, 42)

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Some reviews describe a broad range of experimental findings, but there remains a gap between promising research and established, FDA-approved clinical use