(6) L E Diamond, D C Earle, R C Rosen, et al (2004) Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction International Journal of Impotence Research, Volume 16, pages 5159 (2004)
Major weight loss most likely will not occur in the first week of treatment with a GLP-1
Enhanced plasma half-life and efficacy of engineered human albumin-fused GLP-1 despite enzymatic cleavage of its C-terminal end
Vehicle selection (liposomes, penetration enhancers) meaningfully affects delivery depth
They improve insulin sensitivity, regulate appetite and increase satiety
PMID 32310424