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Mechanistically, paroxetine modulates the structure and function of the gut microbiota, increasing alpha diversity and restoring critical barrier integrity markers such as Mucin 2 (Muc2) and the stem cell marker Lgr5 (Ning et al., 2023

Lower purity products may contain synthesis byproducts, degradation products, or contaminants that reduce effectiveness or introduce safety concerns

Some supplements should be separated for best absorption

Cortisol interferes with collagen synthesis, reduces immune function, and shifts metabolism away from repair processes

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More structural improvementssuch as tendon integrity and joint stabilitytypically develop over 8-16 weeks