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3 It affects more than 700 million people worldwide 4 and leads to the destruction of bone and soft tissue, as well as systemic inflammatory manifestations

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Professor Aronne said these results were encouraging because most participants receiving tirzepatide had a relatively stable weight journey over three years and managed to avoid substantial weight regain. Health Benefits Beyond Weight Loss Clinically significant weight loss is typically defined as losing at least 5% of initial body weight

and hospitalisation for heart failure (RR 0.67 [95% CI 0.64, 0.71]

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