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Intramuscular injection should be used only when this route of administration is necessary, and repeated injections at the same site should be avoided

5.8 Hyperglycemia and Ketoacidosis Due to Insulin Pump Device Malfunction Malfunction of the insulin pump or insulin infusion set or insulin degradation can rapidly lead to hyperglycemia and ketoacidosis

Protein purification XPO1 (also known as CRM1) was purified as described 109 with a minor modification: 4 L of LB medium were used instead of 6 L

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