While orthostatic hypotension is not specifically listed in the UK Summary of Product Characteristics (SmPC) for Mounjaro, hypotension and dehydration are recognised as potential adverse reactions, particularly in patients experiencing gastrointestinal side effects
Combining the peptides would have a net impact of raising the usual GH set point for better lean mass, improved muscle development, better insulin usage, and better metabolic performance (6)
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IV therapy may not be suitable for everyone, and results may vary
In practice, this means most peptide clinics prescribe CJC-1295 and Ipamorelin as a single combined injection or as two injections at the same time each day