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J Phys Chem B 112:44414446
Initially, sUA activates resident liver macrophages, prompting them to produce pro-inflammatory cytokines, including IL-1, IL-6, MCP-1, and TNF-, thereby inducing the migration of circulating monocyte-derived macrophages toward the liver
45,779 Beyond hepatocytes, other liver cell typesincluding LSECs, HSCs, and KCsalso display zonated distributions and functions
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[1] [3] This condition is typically confirmed through blood tests for anti-intrinsic factor antibodies
Some users experience unwanted facial hair growth or systemic effects like heart palpitations
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