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Focus: Managing expectations, emphasizing non-scale victories, continuing protocol despite slower visible progress

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The FDA does not review compounded medications for safety, effectiveness, or manufacturing quality of compounded products

Despite the controversies about the expression of GLP-1R in vascular smooth muscle and endothelial cells, studies have shown that GLP-1RAs have anti-proliferative effects on these cells, and also reduced oxidative stress and increased the production of nitric oxide (NO) (137, 138)

Recent observational studies in nondiabetic weight-loss populations found associations with lower nonexudative AMD diagnoses, but randomized trials would be needed to test prevention

Their absence suggests an incomplete formulation