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While many of these trials were industry-funded, they were still conducted independently

The honest answer is that we do not fully know, and the available evidence cuts in more than one direction

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Statistical significance determined by two-sided unpaired t-tests as indicated or compared to untreated cells (a-d, f-g, k, m, o) or empty vector expressing cells (e)

Arch Gen Psychiatry 61 : 11361144