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This suggests that the antibody may exert a positive influence on energy metabolism and weight regulation by affecting the GIP signaling pathway, potentially achieved by reducing food intake, inhibiting fat storage, or increasing energy expenditure, etc

But they also create a nutritional paradox

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However, unlike GHRP2 and GHRP6, but as growth hormone-releasing hormone (GHRH), ipamorelin does not stimulate the secretion of adrenocorticotropic hormone (ACTH) or cortisol, and is highly selective for inducing the secretion only of GH