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Novo is not alone in investing in combination approaches: in AstraZenecas 2023 announcement of its acquisition of Eccogenes GLP-1 program, the manufacturer noted that they intend to combine the GLP-1 asset with other products in their portfolio (e.g., Farxiga, baxdrostat) in an effort to address obesity comorbidities (e.g., heart disease, kidney disease, metabolic syndrome)

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Brain sections at bregma1 mm ( n = 4 per group) were deparaffinized and treated with xylene and decreasing graded ethanol to distilled water for hydration