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Phase 2 weight loss (48 weeks): 8.7% at 2 mg maintenance 4 mg Weeks 58 First dose where therapeutic effects become clinically meaningful

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In vitro embryo production (IVP) in sheep farming is promising, although optimizing embryo quality and efficiency remains challenging

Generalized pruritus could potentially represent an allergic or hypersensitivity reaction, a dermatologic manifestation of metabolic changes, or an idiosyncratic response

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Strategies include: Eating smaller, more frequent meals Avoiding greasy foods Staying hydrated Consuming adequate protein Including fiber-rich foods gradually If nausea occurs, bland foods such as toast, crackers, bananas, and rice may be easier to tolerate