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Clinically meaningful responses in insulin-resistant patients typically include a reduction in fasting insulin of 20-40% and an improvement in HOMA-IR within 8-12 weeks at therapeutic doses, though individual variability is wide [1]

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Clinical Evidence and Mechanisms of High-Protein Diet-Induced Weight Loss

There is no simple answer for everyone

Chin Med J (Engl) 1983;96:6:445-7

And people who had moderate to severe sleep apnea meaning they stopped breathing multiple times as they slept experienced about 60% fewer events