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Nutrients in the ileum are thought to have a satiating effect, curtailing food intake (249), and GLP-1 is released simultaneously (164)

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In one study, more than half the participants (54%) had no previous use of oral glucose-lowering medication [22], while in another study, all participants were on a stable dose of insulin glargine with (83%) or without (17%) metformin [19]

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Of 412 patients scoped within 6 months of starting treatment, only 8.7% showed erosive esophagitis

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