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Also note that Wegovy is not recommended during pregnancy or breastfeeding

Discontinuation due to adverse events was 4.3-7.1% across tirzepatide doses versus 2.6% placebo

As someone who has spent years in drug development and scaleup, I see in them both the appeal of a clever receptor agonist and the red flags of a product that has largely escaped the discipline of proper clinical development and quality control

Keeping detailed records of symptoms, medical visits, and treatment can also be important if complications arise

Its use for wellness, detoxification, or skin brightening is considered "off-label." Off-label use is a common medical practice where a doctor prescribes a medication for a purpose different from its original FDA approval, based on professional judgment and scientific evidence

Modulation of glutathione S-transferases and glutathione peroxidase by the anticarcinogen butylated hydroxyanisole in murine extrahepatic organs