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Simultaneously, estrogen withdrawal directly worsens insulin sensitivity through its own mechanisms, compounding the metabolic burden that visceral fat accumulation creates
[1] In adults with confirmed GH deficiency, sermorelin may also be considered as a treatment option, although its use in healthy older adults for anti-aging purposes remains unproven and is not an FDA-approved indication
Compounded sublingual semaglutide may be considered by adults who are working with a qualified healthcare provider on medically supervised weight management and who prefer a non-injectable delivery route
Some believe it enhances MT-2 results, though this isn't proven
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