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Ispaghula can be a valuable adjunct to a high-fibre diet and healthy lifestyle, but it is not a substitute for evidence-based medical treatment of metabolic or gastrointestinal disorders

Over time, carriers have shifted from a single broad formulary to more personalized formularies by drug type, tightening criteria and improving cost management

The resulting weight loss that Ozempic patients experienced was a surprising positive side effect, and doctors began prescribing Ozempic to an increasing number of overweight patients without diabetes, a practice known as off-label use. Wegovy, a semaglutide medication also manufactured by Novo Nordisk, is FDA-approved to treat obesity

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The 28.7% average weight loss observed in TRIUMPH 4 places this medication in a category of its own, which should strengthen the case for expedited review