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Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion

According to the instructions of the Annexin V-FITC Apoptosis Detection Kit (Beyotime, C1062), 5 L of Annexin V-FITC reagent was added and gently mixed, followed by the addition of 10 L of propidium iodide staining solution, which was also gently mixed

Int J Mol Sci 24:4268

The principle remains the same: diseased fat must be removed circumferentially with care to remove fat as completely as possible, Su says

Besides reducing appetite, tirzepatide may also improve sugar and fat metabolism

You cannot reasonably expect a positive outcome with the primary treatment if you do not do all in your power to maximize the chances of success