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In addition to a heightened risk of pancreatitis and gallstones, Zepbound patients have also suffered from the following serious gastrointestinal issues: Severe and Prolonged Vomiting While nausea and some vomiting are normal side effects when taking tirzepatide, some patients vomit several times a day for two weeks or more

Rizzo and colleagues also noted that all three patients were taking semaglutide