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Wasted money and lost momentum Beyond the biological risks, there is a practical cost
See our B12 page for more detail
Tests for folate levels should not be carried out unless a full blood count and mean cell volume show and macrocytosis
The methylation cycle does more than just produce SAMe
Eating more protein, dairy, and fewer refined and processed foods is a good start to a more metabolically efficient diet
Olasupo Odunsi, MD, Medical Director Reviewed July 5, 2026 If you're constantly tired and your metabolism feels stuck, low B12 could be part of the problem
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